Monday, July 29, 2013

Increased antibiotic resistance cause for concern: Researchers

http://bangalore.citizenmatters.in/articles/increased-antibiotic-resistance-cause-for-concern-researchers

The World Health Organisation recently announced a ‘global health crisis’ of increased antibiotic resistance. The studies done by WHO have marked India as one of the countries to be suffering from the consequence.

Three medical researchers working as an Associate Professors at R D Gardi Medical College, Ujjain, Dr. Ashish Pathak, Vishal Diwan and Dr. Megha Sharma, conducted a study in Ujjain to get to know the real cause of the problem and to find out solutions for the same. 

Infectious diseases experts raise alarm at growing superbug risk – Louise Milligan | ABC News

 – Louise Milligan | ABC News

http://www.abc.net.au/news/2013-07-24/infectious-diseases-experts-raise-alarm-at-growing-superbug-risk/4841740

Medical experts have raised fears of a new strain of antibiotic-resistant superbug spread through food and even drinking water, and the British chief medical officer has described the superbug threat as ranking with terrorism or global warming. Australia’s chief scientist this month warned antibiotic resistance could mean an end to modern medicine as we know it.

Antibiotic resistance – The last resort - Maryn McKenna | Nature





http://www.nature.com/news/antibiotic-resistance-the-last-resort-1.13426


Thomas Frieden and Sally Davies have recently been speaking publicly about the soaring increase in a little-known class of antibiotic-resistant bacteria: carbapenem-resistant Enterobacteriaceae (CREs). Davies, the United Kingdom’s chief medical officer, described CREs as a risk as serious as terrorism (see Nature 495, 141; 2013). “We have a very serious problem, and we need to sound an alarm,” said Frieden, director of the US Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia.
Their dire phrasing was warranted. CREs cause bladder, lung and blood infections that can spiral into life-threatening septic shock. They evade the action of almost all antibiotics — including the carbapenems, which are considered drugs of last resort — and they kill up to half of all patients who contract them. In the United States, these bacteria have been found in 4% of all hospitals and 18% of those that offer long-term critical care.

Monday, July 15, 2013

Monday, May 13, 2013

Global Scenario of Bacteria, Infections, Antibiotics and Resistance- By Dr. A. J. Tamhankar (Research Associate: Sandeep Nerkar)

Unprecedented Insight Into Causes Of Pneumococcal Disease Offered By Genome Sequencing

Tuesday, April 30, 2013

Global Action Plan for the Prevention and Control of Pneumonia and Diarrhoea (GAPPD)


The CaT Secretariat is sharing the attached editorial from Margaret Chan (WHO) and Tony Lake (UNICEF) and links for the complete documents on the Global Action Plan for the Prevention and Control of Pneumonia and Diarrhoea (GAPPD) which have now been released:
Related to this, the Lancet series of papers on Pneumonia and Diarrhoea can be accessed at:
There has also been a lot of media coverage - selected articles which may be of particular interest include the following:
  
BLOG from Seth Berkley: 
Statement of support: 
We would like to highlight that CaT Member, Dr Zulfi Bhutta, played a leading role in development of the GAPPD.
The CaTS was consulted during the early development of this document and we appreciate the effort made by Dr Osman Mansoor to include CaT.
As with the Global Vaccine Action Plan (GVAP), as country and regional discussions are initiated, lets all work to assure that the control and prevention of enteric fever and in particular typhoid and paratyphoid fever is included in the GAPPD work plans, as appropriate.

Article:

Some 19000 children under the age of 5 years die each and every day, with 5500 of these deaths caused by pneumonia and diarrhoea. These are not mere statistics. 2 million young lives are lost each year from these two eminently preventable causes of death.This situation is completely unacceptable. Despite the fact that the basic elements needed to reduce childhood deaths from pneumonia and diarrhoea are well known and of low cost, current coverage is appallingly low.

We welcome the Lancet Series on Childhood Pneumonia and Diarrhoea.The Series provides the evidence base to make the case that ending preventable child deaths from pneumonia and diarrhoea within the next 12 years is ambitious but achievable and necessary. Momentum to reduce child mortality continues to build, and it is imperative for the world’s children that we take advantage of this opportunity.

As we approach the 1000-day mark before the Millennium Development Goal deadline, a raft of interconnected initiatives provides a platform to accelerate progress. The UN Secretary-General’s widely endorsed Global Strategy for Women’s and Children’s Health aims to save 16 million lives through a “continuum of care” approach; a Global Vaccine Action Plan is working towards universal access to immunisation by 2020; more than 170 countries have signed on to A Promise Renewed, the call to action spearheaded by the Governments of Ethiopia and India, UNICEF, and USAID to end all preventable child deaths by 2035; and the UN Commission on Life-Saving Commodities for Women and Children is helping to improve access to priority medicines.

In this context, it is critical to intensify efforts to tackle pneumonia and diarrhoea—the two biggest killers of children younger than 5 years after the newborn period, which account for about 29% of all under-5 deaths. A new WHO/UNICEF Integrated Global Action Plan for the Prevention and Control of Pneumonia and Diarrhoea5 aims to help countries meet this goal by establishing healthy environments to protect children from pneumonia and diarrhoea and by increasing access to cost-effective interventions for both prevention and treatment.

 The Integrated Plan builds upon two previous plans from 2009: the Global Action Plan for the Prevention and Control of Pneumonia6 and Why Children are Still Dying and What Can be Done,7 a seven-point plan for comprehensive diarrhoea control. We have encouraged the use of cost-eff ective prevention—eg, exclusive breastfeeding, vaccines, and access to clean water—and treatment with simple, inexpensive antibiotics, oral rehydration salts, and zinc. Now we must help countries unplug the bottlenecks that are keeping these services from the children who need them.

Children who are poor, hungry, and living in remote areas are most likely to suffer from these “forgotten killers”, and the burden that pneumonia and diarrhoea places on their families and on health systems aggravates existing inequalities. Identifying the children at greatest risk, who are the hardest to reach and the most neglected, and targeting them with interventions that are proven to work will close the gap and end these entirely preventable deaths. Better coordination and integration are key to tackling pneumonia and diarrhoea. The determinants that underlie these diseases are often the same. The children at risk of diarrhoea are the same ones at risk of pneumonia.

 The strategies for prevention are similar, and the places where systems need strengthening to deliver services in communities, clinics, and hospitals are also common to both diseases. The Integrated Plan makes a strong case for more efficient integration and identifies key steps to be taken. It will help countries to analyse local data, act on the results, and monitor progress towards clear, achievable goals. This requires a concerted effort to use a systematic approach of sharpening evidence-based planning and implementation at all levels, and ensuring eff ective systems of monitoring and accountability for results, within existing frameworks such as the Commission on Information and Accountability for Women’s and Children’s Health and Countdown to 2015.

We must also build on lessons learned and the good practices and innovations that some countries have been applying, which include strengthening primary care; removing financial barriers to access; expanding the role of non-governmental providers; establishing public private partnerships; and making use of new mobile.This is not a job for the health sector alone. Successful implementation of the Integrated Plan requires engagement of families, health-care providers, and key actors in water and sanitation. There must also be strong cooperation among UN agencies, national governments, and the private sector. And it must begin today.

Margaret Chan, *Anthony Lake
WHO, Geneva, Switzerland (MC); and UNICEF, New York, NY 10017,
USA (AL)
alake@unicef.org
technologies to achieve sustainable, quality services.

Tuesday, April 23, 2013

Protect your world - get vaccinated









To highlight the extensive body of knowledge collected in developing the Global Vaccine Action Plan (GVAP), the journal Vaccine today released a special supplement dedicated in full to the Decade of Vaccines. This supplement includes the complete GVAP, a foreword by the DoVC Leadership Council, an editorial by the Steering Committee Co-Chairs and members of the DoVC Secretariat and 27 companion documents that link with the GVAP six strategic objectives.

At the heart of the GVAP for the decade and beyond will be equity, collaboration, innovation and country ownership, so that every individual can have access to life-saving vaccines. The series of papers published in this supplement were commissioned to further explore these themes. It is our hope that stakeholders will use the knowledge collected here in developing their own strategies for realizing the ambitious goals set for the decade.

As this is our final message, we hope that you will join countries around the globe to celebrate World Immunization Week 2013 (20-30 April). There truly is a collaborative push towards achieving universal and equitable access to vaccines.


World Immunization Week 2013

The global slogan for this year’s world immunization campaign is “Protect your world - get vaccinated”. Regional themes are:
  • Africa:  Save lives, Prevent disabilities, Vaccinate!
  • Americas: Vaccination, a shared responsibility
  • Eastern Mediterranean: Stop measles now!
  • Europe: Protect. Prevent. Immunize.
  • South-East Asia: Intensification of routine immunization
  • Western Pacific: Finish the job – no more measles for anyone.                                             
  • Topics included in the supplement: The needs, challenges and opportunities in development; delivery and costing; health benefits; vaccine technologies; science based regulations; public and political support; pricing and procurement; implementation research and health systems; introduction of new vaccines; vaccine supply and logistics systems; equity and perspectives of civil society, developing countries, and vaccine manufacturers in developed and developing countries 

Read The ``TRUE LIFE STORY``of a family infected with MRSA