Wednesday, October 28, 2015

Contributed by Siddarth David & Dr. Tamhankar

A study published in the published in the Journal of the Paediatric Infectious Diseases Society has shown rising rate of infections, particularly prevalent among children between under the age of 5. After analysing a nationwide data base of reports from microbiology laboratories from 1991-2011, the study showed the increase of prevalence of "extended-spectrum beta-lactamase" (ESBL) producing bacteria and resistance to third-generation cephalosporins was highest among children under 5 years.


This means treatment with last-resort antibiotics such as carbapenems translating to longer hospital stays, higher health care costs, and increased mortality. The Centres for Disease Control (CDC) in the US, had called for stronger steps to counter ESBL-producing bacteria in 2013, given the significant threat they pose to public health in the US. The study also calls for more research into defining the risk factors for these infections in children, their prevalence in different settings, and their molecular epidemiology. 

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