Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

Living Caulobacter runaway from dying Caulobacter bacteria.-Exposure to the extracellular DNA (eDNA) released by dying neighboring bacteria stops the sticky holdfasts of living Caulobacter from adhering to surfaces, preventing cells from joining bacterial biofilms. Less sticky cells are more likely to escape established colonies, out to where conditions may be better. http://www.medicalnewstoday.com/articles/193426.php
Abbott has received clearance from the U.S. Food and Drug Administration to market a new, sensitive molecular diagnostic test and instrument to simultaneously detect two sexually transmitted diseases (STDs), gonorrhea and chlamydia, including a new variant strain of chlamydia recently discovered in Sweden.
http://www.medicalnewstoday.com/articles/193258.php
A commonly used bone marrow stem cell may be able to help treat sepsis, a deadly condition that can occur when an infection spreads throughout the body.
http://www.medicalnewstoday.com/articles/193499.php
Scientists studying MRSA have identified one of the components responsible for making it so deadly.
http://www.medicalnewstoday.com/articles/193631.php
Bees could have a key role to play in urgently-needed new treatments to fight virulent MRSA,. A substance known as beeglue or propolis, originating from beehives in the Pacific region, is active against MRSA, which causes potentially fatal infections, particularly in hospital patients.
http://www.medicalnewstoday.com/articles/193275.php
American Veterinary Medical Association (AVMA) and FDA committed to working together to address antimicrobial resistance concerns in USA. http://www.medicalnewstoday.com/articles/193376.php
A modest behavioral intervention program averaging just 35 minutes can measurably reduce the incidence of HIV and sexually transmitted infections (STIs) among female sex workers.
http://www.medicalnewstoday.com/articles/193475.php
Gen-Probe has announced that it has received a European CE mark for its APTIMA® assay for Trichomonas vaginalis, a common parasitic sexually transmitted disease.
http://www.medicalnewstoday.com/articles/193776.php
Ecolab Launches First EPA-Approved, Ready-to-Use Hard Surface Disinfectant Effective Against Clostridium Difficile http://www.medicalnewstoday.com/articles/193722.php
New antibiotics: from honey bees called defensin-1, which could one day be used to treat burns and skin infections and to develop new drugs that could combat antibiotic-resistant infections. http://www.medicalnewstoday.com/articles/193584.php
Washington State University and the Gates Foundation form new School for Global Animal Health. for investigating emerging disease. From Avian influenza, to West Nile virus.
http://www.medicalnewstoday.com/articles/193284.php
ABR Workshop in Nairobi, Kenya and A Curriculum for Community Action on AMR
http://www.reactgroup.org/files/docs/ReAct%20Quarterly%20no%202_2010.pdf
CDC has published guidelines to address gram-negative bacteria http://www.cdc.gov/ncidod/dhqp/gram-negativeBacterial.html
Fighting Hospital Infections http://www.newschannel5.com/global/story.asp?s=11566833
Modified CO2 processing may render microbes ineffective and extend shelf life of foods
http://www.foodproductiondaily.com/Processing/CO2-process-could-herald-new-dawn-for-heat-sensitive-liquids
Eating chicken or steak in USA means consuming pharmaceuticals not required by body
http://www.slashfood.com/2010/07/01/are-farm-animals-headed-to-rehab/

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-APP Pharmaceuticals, Inc., a wholly owned subsidiary of Fresenius Kabi Pharmaceuticals Holding, Inc., (NASDAQ: APCVZ) announced that it has received approval from the U.S. Food and Drug Administration (FDA) to market Aztreonam for Injection, USP in two dosage strengths. Aztreonam is therapeutically equivalent to the reference-listed drug Azactam®, which is marketed by Bristol-Myers Squibb.

-Sampling of pigeons captured on the streets of Madrid has revealed that Chlamydophila psittaci and Campylobacter jejuni were highly prevalent in the bird population, , both of which cause illness in humans-e.g.Diorrhea.

-Scientists have completed the most comprehensive comparative analysis to date of bacterial communities inhabiting the human nose and throat, which could provide new insights into why some individuals become colonized with pathogens while others do not. They released their findings in mBio™ the online open-access journal published by the American Society for Microbiology.

-shift in the balance between the "good" bacteria and the "bad" bacteria that populate our gut could be a harbinger of colon cancer.

-Discovery Of the mechanisms by which pathogenic bacterial populations control the way they spread over the surface of the organs they infect and stop when they detect the presence of an antibiotic, Could Help To Design New Strategies To Increase Their Sensitivity To Antibiotics.

-Hospira Receives FDA Approval For Meropenem For Injection, USP (I.V.)

-New, high-powered genomic analytical techniques have established that as many as 1,000 different single-celled species coexist in relative harmony in every healthy human gut.

-United States (U.S.) CDC has issued new and important guidelines on the detection of Mycobacterium tuberculosis infections, the causative agent of tuberculosis (TB). In these landmark guidelines, CDC advises that Interferon Gamma Release Assay (IGRA) blood tests are now preferred over the 100+-year-old tuberculin skin test (TST) for diagnosing TB infection in certain populations

-Survival Rate Up To 100% For Late Stage Treatment Of Anthrax Infections

-A new study indicates different delivery methods of newborn babies has a big effect on the types of microbial communities they harbor

-In a bid to reduce levels of the sexually transmitted infection (STI) chlamydia among young people in London, sexual health charity Terrence Higgins Trust will be inviting young people attending this year's Pride London to take a free chlamydia test during their day out.
-FDA seeks less use of antibiotics in animals to keep them effective for humans (The Washington post)
-News from Europe-A cross-border project including MRSA surveillance and prophylaxis is launched in the European Region of Maas-Rhein, a region including parts of Germany, Belgium and the Netherlands; Norway –New routines for how to report a patient with previously diagnosed MRSA, when he/she is again found positive suggested. Denmark- Decision for stopping the use of cephalosporins in pig farming and doctors demand tougher rules for veterinary AB use; the head of doctors’ union points out that in Denmark 130 tons of ABs are used annually for animals, while only 48 tons for humans. ; Comparison of the sales of veterinary antibacterial agents between 10 European countries

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-New antibiotics-Antibacterial NXL103 (flopristin/linopristin) starts Phase II clinical trial--- Novexel, a speciality pharmaceutical company focused on the discovery and development of novel antibiotics designed to overcome the significant global problem of microbial resistance, announces that its most advanced oral antibacterial NXL103 (flopristin/linopristin), has started a Phase II clinical trial in adults with acute bacterial skin and skin structure infections (ABSSSI). The trial is designed to assess the safety and efficacy of NXL103 in comparison to oral linezolid.
- Eschar With Cellulitis as a Clinical Predictor in Community-Acquired Methicillin-Resistant Staphylococcus Aureus (MRSA) Skin Abscess -A central black eschar with cellulitis has good specificity and high positive predictive value in diagnosing CA-MRSA infection. (The Journal of Emergency Medicine, May 2010)
-'Hidden' tuberculosis raises drug-resistance fears ;New study doubles known rate of infection at a South African hospital.
-MRSA in Patients With Cystic Fibrosis Linked to Shorter Survival Time (CME)
-Extensive Drug Resistance found in Malaria and Tuberculosis
-Tackling antimicrobial resistance- WHO Patient Safety is working towards finding solutions how best to support ongoing international activities to address AMR. Activities are also ongoing to finalize an AMR work plan document during the first half of 2010.
-Bacterial Burden and Wound Outcomes as Influenced by Negative Pressure Wound Therapy
-Vancomycin Dosing: Guidance for Clinicians
-Infection Control Practices in Ambulatory Surgical Centers
-Contraceptive Use to stop infections: New Clinical Guidance From the CDC

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-Advanced Life Sciences Holdings, Inc. , a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, announced the expansion of its collaboration with the U.S. Government to include the evaluation of Restanza's activity against sexually transmitted infections (STI's), such as gonorrhea.
-Multiple imaging agents with a hybrid imaging technique can be a valuable tool for accurately diagnosing and determining treatment for a variety of diabetes-associated foot diseases.
-What Is A Cryptosporidium Infection (Cryptosporidiosis)? What Causes A Cryptosporidium Infection (Cryptosporidiosis)?
-A team from the Michael G. DeGroote Institute for Infectious Disease Research has revealed that a small chemical, made by the superbug Staphylococcus aureus and its drug-resistant forms, determines this disease's strength and ability to infect.
-Electronic health records can significantly shorten treatment times for patients diagnosed with chlamydia,
-In a clinical trial involving HIV-negative volunteers with early-stage syphilis, researchers have found that azithromycin pills are as effective as penicillin injections in curing early-stage syphilis. -Biosensors Reveal How Single Bacterium Gets The Message To Split Into A Swimming And A Stay-Put Cell
-Keyboards located in triage and registration areas were found to be more contaminated with bacteria than those in other areas of the Emergency Department, "Contamination was predominantly found in non-treatment areas,"
-BD Announces First FDA-Cleared Assay On The BD MAX™ System To Detect Group B Streptococcus
-Researchers have discovered a new strain of bacteria that help degrade polycyclic aromatic hydrocarbons, environmental pollutants that are the most harmful aspects of oil spills.
-HPA Urges Fans To practise safe sex, by using a condom, to reduce the risk of contracting sexually transmitted infection while in South Africa for The World Cup."
-Eliminating Catheter-associated Urinary Tract Infections: Avoid Catheter Use
-How Bacteria Make Syringesto inject virulence factors directly into the host cell.
-Texas Tech University announced Wednesday the signing of an exclusive worldwide license agreement for a chemical additive called an aptamer that makes certain existing antibiotics viable against antibiotic-resistant bacteria.
-Center for Global Development (CGD) report. while talking of The Race Against Drug Resistance says The growing threat of drug resistance, which will increasingly leave more and more people vulnerable to diseases that were once easier to treat, requires a systematic global response, and says further that the Global Drug Distribution Programs is One Factor In Hastening Drug Resistance.
-Risk Factors for Antibiotic-Resistant Escherichia coli Carriage in Young Children in Peru: Community-Based Cross-Sectional Prevalence Study
-Researchers have found antibiotic-resistant bacteria in seven species of sharks and redfish captured in waters off Belize, Florida, Louisiana and Massachusetts in USA.
-Scientists Watch As E. Coli Bacteria Evolve Heat Resistance Under Stress
-Altered Virus Becomes Medicine

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis
-American Society for Microbiology Comments on Antimicrobial Resistance
-PhD student position at the Center for Systems Microbiology,Technical University Denmark:
The project is aimed at improving our understanding of how antibiotic resistance develops in microbial communities, including the human microbiome, and how human genetic host factors influence microbiome composition and its antibiotic resistance.
-TWO PHD STUDENT POSITIONS IN MICROBIOLOGY IN THE AREA OF GENETIC AND PHYSIOLOGICAL ASPECTS OF ANTIBIOTIC RESISTANCE DEVELOPMENT IN BACTERIA.
-Why Do Beta-Lactams Cause Rashes?
-A Fast and Highly Sensitive Blood Culture PCR Method for Clinical Detection of Salmonella Enterica Serovar Typhi
-LRSA---Spanish Hospital Sees Outbreak of Linezolid-Resistant Staphylococcus Aureus
-Worst hospitals in Britain for HAI-superbugs
-American Medical Association (AMA) proposes a multi-faceted approach to combating antibiotic resistance
-Several American Health care societies join together to develop new Guidelines for the Prevention of Antimicrobial Resistance in Hospitals
-Effect of antibiotics in the environment on microbial populations.
-Using an advanced genetic screening technique- DNA microarray technology, ARS-USA has detected over 700 genes that give microbes like Salmonella, E. coli, Campylobacter, Listeria, and Enterococcus the ability to resist antibiotics and other antimicrobial compounds.
-Protein CCL5 may fight against tuberculosis
-Newly released IFT Expert Report elucidates the implications of antimicrobial uses throughout the food system.
-Health implication of urine therapy practiced in Africa
-Talking to Female Patients About Sexual Health: Overcoming Common Communication Challenges

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-Azithromycin May Not Improve Lung Function in Patients With CF Uninfected With Pseudomonas aeruginosa
- Predicting Colorectal Cancer With The Help Of Bacteria -Recent findings suggest that bacteria residing in the the human intestinal tract may be associated with an individual's risk of developing colon cancer. Say Scientists from the University of Florida
-New Bacterial Signaling Molecule Could Lead To Improved Vaccines.
-Early Antibiotic Treatment Associated With Improved Outcomes For Patients With Acute Exacerbations Of COPD
-An active compound - plectasin - found in fungi and lower animals could well be an effective weapon against hazardous bacteria. Plectasin, a small protein molecule, can even destroy extremely resistant bacteria . Scientists at the Universities of Bonn, Utrecht, Aalborg and of the Danish company Novozymes AS are able to explain how the substance does this. The researchers believe plectasin is a promising lead compound for new antibiotics.
-AdvanDx To Offer BinaxNOW® PBP2a Test For Rapid Detection Of PBP2a In Methicillin-Resistant Staphylococcus Aureus (MRSA)
-Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) announced the presentation of preclinical data on novel monoclonal antibodies against toxins produced by the bacterium Clostridium difficile (C. difficile).
-Unlocking The Keys To H. pylori's Helical Structure May Lead To Better Antibiotic Drugs For Diseases From Ulcers To Diarrhea And Cholera : Say researchers at Fred Hutchinson Cancer Research Center.
-Researchers in the US have developed a new type of treatment that could herald a new approach to fighting infectious diseases that stimulates the immune system to protect the body against a range of bacteria instead of relying on antibiotics to attack them directly, (which leads to the emergence of resistant strains of pathogens.
-A defective, mutant strain of the bacterium that causes gum disease could provide a clue to potential treatments for Alzheimer's, Parkinson's and a number of other diseases. Say Researchers from the University of Florida
http://www.medicalnewstoday.com/articles/189933.php
-A new "tree of life" has been constructed by researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech for the gamma-proteobacteria, a large group of medically and scientifically important bacteria that includes Escherichia coli, Salmonella typhimurium, and other disease-causing organisms.
-A research appearing in Nature, with the participation of doctors Susana Campoy and Jordi Barbé from the Department of Genetics and Microbiology at Universitat Autònoma de Barcelona, demonstrates that bacteria have a surprising mechanism to transfer virulent genes causing infections. The research describes an unprecedented evolutionary adaptation and could contribute to finding new ways of treating and preventing bacterial infections.
-The Human Microbiome Project (HMP) has published an analysis of 178 genomes from microbes that live in or on the human body.
-What Is Cholera? What Causes Cholera?
-US Army scientists have discovered a way to "trick" the bacterium that causes anthrax into shedding its protective covering, making it easier for the body's immune system to mount a defense. The study, which appears in this month's issue of the journal MICROBIOLOGY, could lead to new approaches for treating anthrax infection.
-Prevention strategies for antimicrobial resistance: A review
-ReAct Urges Transatlantic Taskforce to take Global Approach on AMR
-UK – new PM Cameron: HAI figures to be published every week, for every hospital – move to give patients the ability to choose according to performance of NHS hospitals - Telegraph

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-FDA Approval Of Bacitracin For Injection, USP
-Response To Vaccines Could Depend On Your Sex
-Initiative seeks billions of dollars to develop promising drugs and vaccines for neglected diseases such as tuberculosis and dengue fever.
--Scientists are reporting success in a first attempt to silence the biochemical conversations that disease-causing bacteria use to marshal their forces and cause infections. In a study in ACS' monthly journal, Biomacromolecules, they describe use of specially designed plastic-like materials to soak up the substances that bacteria produce and pass to one another as messages.
-An international team led by a University of Cincinnati (UC) researcher has shown how a bacterial community evolves to survive hostile host defenses in the body.
-Dramatic surge seen in kids hospitalized with MRSA in USA
-WHO – Sweden pushes the AB resistance question at WHO’s WHA

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-Micro Identification Technologies In The Fight Against Bacteria
-UT Southwestern researchers find mechanism that may stop E coli from developing in cattle: (Proceedings of the National Academy of Sciences)
-CrystalGenomics Announces Successful Completion of a Phase I SAD Clinical Trial for CG400549, its Novel Antibiotic Candidate-
-Natura World Introduces Anti-Microbial, Anti-Viral Mattresses
-Effect of antibiotic prescribing in primary care on antimicrobial resistance in individual patients: systematic review and meta-analysis
-New antibiotics to tackle multidrug resistant bacteria are much needed. Chantal Morel and Elias Mossialos show how financial incentives might be used to persuade drug companies to develop New Antibiotics------The twin challenge of conserving the effectiveness of existing antibacterial drugs and developing new ones
-Two-Thirds Of Child Deaths In 2008 Due To Infectious Diseases

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-A bacteria can communicate with yeast to block the development of drug-resistant yeast infections, (May issue of Microbiology) to prevent hospital-acquired infections associated with medical implants.
-Role Of Human Behavior In Infectious Disease Emergence
-Computer Model May Improve Detection of Serious Bacterial Infection in Young Children With Fever
-Questionnaire for Case Studies to diagnose Resistance in clinics.
-An Extra Layer Of Protection For Bacterial Spores Discovered By Biologists
-Hand washing prevents the spread of water-borne disease in Africa. Environmental Science & Technology.
-Infection Disease specialist Dr Spellberg of UCLA briefs, on initiative of IDSA to Republican Matheson, who also promotes the STAAR Act (Strategies to Address Antibiotic Resistance)

Global scenario of microbes, infections, antibiotics and resistance - By Dr. A.J. Tamhankar

-Using technology an Iowa State University researcher is working on a faster method to detect and genetically identify salmonella from contaminated foods.

-Simplifying Treatment Of A Serious Eye Infection (Bacterial keratitis)

-Potent anti-microbial proteins discovered in platypus

-NASA studies bacteria in space-flight

-Transfer of Carbapenem-Resistant Plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in Patient

-MRSA Survivors Network to raise awareness on MRSA infections